該期刊發表了最初研究的結果，這些研究被認為有可能在最廣泛的意義上促進生理學。關于病理生理學或方法論主題的論文也將被考慮，因為它們所包含的信息可以作為進一步研究生理機制的工具。換句話說，他們的主題必須清楚地傳達一個生理信息。純臨床論文將被排除在外。簡短的通訊是保留出版的前沿材料，尚未以完整的紙張形式，但我們的讀者立即感興趣。文章應包括一項聲明，說明實驗符合進行試驗的國家現行法律。

The Journal publishes the results of original research considered likely to further the physiological sciences in their broadest sense. Papers on pathophysiological or methodological topics will also be considered in so far as the information they contain can be used as a tool for further investigation of physiological mechanisms. In other words their subject matter must clearly convey a physiological message. Purely clinical papers will be excluded. Short communications are reserved for the publication of forefront material not yet in full paper form but of immediate interest to our readers. Articles should include a declaration to the effect that the experiments comply with the current laws of the country in which the experiments were performed.